在水果中发现的生物活性化合物的骨质效应在介质细胞干细胞上:一篇评论
Lia Igel Sodré1, Maria Eduarda Cordebello Gall2, Monique de Barros Elias3
1Graduate Program in Science of Nutrition, Fluminense Federal University, Niterói, RJ 24020-140, Brazil.
Nutrition reviews
|January 25, 2025
概括
水果中的植物化学物质通过增强介质干细胞再生和骨质生成来促进骨健康. 需要进一步的研究来确定最佳的治疗剂量和骨疾病治疗的人类安全.
科学领域:
- 生物化学和分子生物学
- 细胞生物学 细胞生物学
- 营养科学 营养科学
背景情况:
- 植物化学物质具有有益于人类健康的抗炎,抗氧化和抗癌性质.
- 生物活性化合物影响细胞信号通路,参与增殖,炎症和免疫反应.
- 某些植物化学物质通过激活特定的信号通路来刺激骨质生成,骨形成和矿化.
研究的目的:
- 识别水果中的生物活性化合物对介质细胞干细胞具有骨质效应.
- 阐明水果衍生植物化学物质骨质效应背后的机制.
主要方法:
- 进行了系统的文献审查.
- 搜索的数据库:LILACS,MEDLINE,以及PubMed. 这些数据库中搜索的
- 包括2014年至2024年间发表的34篇文章.
主要成果:
- 植物化学物质增强介质干细胞再生,包括增殖和骨质分化.
- 生物活性化合物促进细胞外基质的形成和血管生成因子的分泌.
- 有证据支持水果植物化学物质在骨形成和矿化中的作用.
结论:
- 来自水果的植物化学物质显示出预防和治疗骨疾病的潜力.
- 需要进一步的研究来确定治疗剂量,人体机制和安全性.
- 优化植物化学品的使用可以显著改善骨健康结果.
更多相关视频
09:30Mesenchymal Stem Cell Isolation from Pulp Tissue and Co-Culture with Cancer Cells to Study Their Interactions
Published on: January 7, 2019
10.3K
08:11Construction and Use of an Electrical Stimulation Chamber for Enhancing Osteogenic Differentiation in Mesenchymal Stem/Stromal Cells In Vitro
Published on: January 31, 2019
11.1K
相关概念视频
Mesenchymal Stem Cells
4.5K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
4.5K
Source And Potency Of Stem Cells
5.0K
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
5.0K
Stem Cell Therapy for Tissue Regeneration
3.8K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
3.8K
