Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Correlation between ECG and Cardiac Cycle01:25

Correlation between ECG and Cardiac Cycle

3.3K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
3.3K
Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

886
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
886
Electrocardiogram01:29

Electrocardiogram

2.1K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
2.1K
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers01:12

Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers

894
Class III antiarrhythmic drugs are a group of medications that can prolong action potentials in the heart. They achieve this by blocking potassium channels or enhancing inward currents from sodium channels. However, these drugs have a unique property of "reverse use-dependence," which is most pronounced at slower heart rates and can lead to torsades de pointes—a specific type of arrhythmia. However, it is essential to note that excessive QT interval prolongation—a measure of...
894
Cardiac Action Potential01:30

Cardiac Action Potential

897
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
897
Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers01:22

Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers

1.2K
Class I antiarrhythmic drugs are used to treat various types of arrhythmias or irregular heart rhythms. These drugs block the sodium (Na+) channels in the cardiac cells, thereby affecting the movement of electrical impulses across the heart. Class I antiarrhythmic drugs are divided into three subgroups: Class IA, Class IB, and Class IC, each with distinct mechanisms of action and effects on the heart.
Class 1A Antiarrhythmic Drugs: These drugs work by moderately blocking sodium channels,...
1.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Heterogeneity in endpoints, monitoring methods and blanking periods in clinical trials of atrial fibrillation ablation: a systematic review and meta-analysis.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026
Same author

Genetics of supraventricular tachycardia: current evidence with a focus on translational relevance and personalized medicine.

Frontiers in cardiovascular medicine·2026
Same author

Late Fracture of Stylet-driven Lead Intended for Conduction System Pacing 2 Years After Implant.

The Journal of innovations in cardiac rhythm management·2026
Same author

Giving Voice to Head and Neck Cancer Survivors: A Qualitative Investigation Into the Utility of Peer Support.

ANZ journal of surgery·2026
Same author

The role of exercise in reducing vasovagal syncope recurrence: A systematic review and meta-analysis.

American journal of preventive cardiology·2026
Same author

Safety and Efficacy of Pulsed Field Ablation for Atrial Fibrillation in Older Patients: An Observational Study at a Large Tertiary Centre in Australia.

Journal of arrhythmia·2026

相关实验视频

Updated: May 30, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.4K

如何纠正心脏再同步治疗后的QT间隔.

Amin Esmailian1, Colin Machado2, Hui Chen Han3

  • 1Victorian Heart Institute, Monash University, Clayton, VIC, Australia.

Journal of electrocardiology
|January 25, 2025
PubMed
概括

在心脏再同步治疗 (CRT) 后,纠正QT (QTc) 间隔的不同公式产生了不同的结果. 博戈西安-霍奇斯和劳塔哈朱-弗雷德里西亚组合在心力衰竭患者中提供一致的QTc测量.

关键词:
捆绑一个分支区块.心脏再同步治疗心脏再同步治疗纠正了QT时间.时间间隔 JT JT 间隔QRS的持续时间在 QT 间隔.

更多相关视频

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

378
Electrocardiogram Recordings in Anesthetized Mice using Lead II
04:16

Electrocardiogram Recordings in Anesthetized Mice using Lead II

Published on: June 20, 2020

12.6K

相关实验视频

Last Updated: May 30, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.4K
Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

378
Electrocardiogram Recordings in Anesthetized Mice using Lead II
04:16

Electrocardiogram Recordings in Anesthetized Mice using Lead II

Published on: June 20, 2020

12.6K

科学领域:

  • 心脏病学 心脏病学
  • 生物医学工程 生物医学工程

背景情况:

  • 在心力衰竭患者中,QT间隔异常至关重要.
  • 心脏再同步疗法 (CRT) 对电生理学参数产生影响.
  • 准确的QT间隔校正对于风险分层至关重要.

研究的目的:

  • 在CRT后评估各种QT间隔校正公式.
  • 找出可靠的方法来计算具有广泛QRS复合体的CRT患者的纠正QT (QTc).

主要方法:

  • 包括严重心力衰竭患者与左捆分支阻塞接受CRT.
  • 在CRT前后测量QT间隔.
  • 应用了多种配方 (博戈西安,巴塞特,霍奇斯,劳塔哈朱,弗雷德里西亚等) 用于QTc计算.

主要成果:

  • CRT显著减少了QRS持续时间.
  • 巴塞特的配方在CRT后没有显著的QTc变化.
  • 博戈西安-霍奇斯和劳塔哈朱-弗雷德里西亚的公式产生了可比且一致的QTc间隔.

结论:

  • 配方选择显著影响CRT患者的QTc值.
  • 建议使用Bogossian-Hodges和Rautaharju-Fredericia组合来进行一致的QTc评估.
  • 这些QTc校正方法的进一步验证是有必要的.