怀孕前和怀孕期间健康的生活方式,以预防儿童肥胖:研究协议的平行组随机试验 - - PRE-STORK试验试验
Nina Kornerup1, Julie Hagstrøm Danielsen1, Ronni Eg Sahl1
1Clinical and Translational Research, Steno Diabetes Center Copenhagen, Herlev, Denmark.
BMJ open
|January 25, 2025
概括
这项研究调查了超重孕妇的生活方式干预措施,以预防儿童肥胖. 该PRE-STORK试验旨在通过预孕和产前护理来减少新生儿肥胖.
科学领域:
- 生殖健康 生殖健康
- 儿科卫生健康 儿科卫生健康
- 公共卫生 公共卫生
背景情况:
- 全球超重的发病率增加了三倍,超过40%的丹麦妇女怀孕时超重.
- 母亲超重和过度妊娠体重增加是儿童肥胖的危险因素.
- 怀孕期间目前的生活方式干预措施对儿童健康结果的影响有限.
研究的目的:
- 评估一种生活方式干预对新生儿肥胖症的影响,对患有超重或肥胖的母亲出生的儿童.
- 评估预孕和产前生活方式干预对预防儿童肥胖的影响.
- 建立一个出生队列,长期监测儿童健康情况,直到18岁.
主要方法:
- 随机对照试验包括360名女性 (BMI 25-44 kg/m2;年龄18-40岁) 和他们的伴侣.
- 干预组在怀孕前和怀孕期间接受生活方式指导 (减肥,运动,饮食,指导).
- 主要结局:出生时新生儿肥胖的差异;次要:长期监测儿童的健康状况.
主要成果:
- 关于新生儿肥胖的初级结局数据正在等待.
- 关于儿童长期健康的二次结果数据正在等待.
- 该研究正在积极招募参与者.
结论:
- 该PRE-STORK试验将为预防儿童肥胖的有效策略提供关键的见解.
- 调查结果可以为公共卫生政策和对母婴健康的临床指南提供信息.
- 这项研究强调了怀孕前护理在应对儿童肥胖率上升方面的重要性.
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