在健康的胸前大动脉中,通过大模拟,转变为动的特征
Kuiyu Cheng1, Shehnaz Akhtar1, Kwan Yong Lee2,3
1School of Mechanical Engineering, University of Ulsan, Ulsan, 44610, Republic of Korea.
Scientific reports
|January 25, 2025
概括
这项研究使用计算流体动力学揭示了动脉中血流如何从平滑过渡到动荡. 这种流,特别是在大动脉中,可能会导致诸如动脉样硬化等血管疾病.
科学领域:
- 心血管科学 心血管科学
- 流体动力学 流体动力学
- 生物医学工程 生物医学工程
背景情况:
- 了解血液流动的动态对于诊断和治疗心血管疾病至关重要.
- 大动脉中的过渡流可以影响诸如动脉样硬化和大动脉剖析等疾病的发展.
研究的目的:
- 在理想化的胸前大动脉模型中研究过渡性流动特性.
- 分析血液动力学参数及其与血管疾病发展的关系.
主要方法:
- 采用大模拟 (LES) 和适应墙壁的局部粘度 (WALE) 模型.
- 使用OpenFOAM溶解器 (pimpleFoam) 来进行不可压缩的牛顿流体模拟.
- 进行了超过30个心脏周期的模拟,并对统计可靠性进行了整体平均.
主要成果:
- 动荡源于高峰后的动脉,在减速阶段进一步发展.
- 流的最大强度超过了25%,大动脉门和下降大动脉的显著发展.
- 观察到高壁切削应力 (WSS) 在缩的高峰期 (高达30Pa) 和低,振荡式WSS在腹痛期.
结论:
- 这项研究阐明了胸前动脉中从层状流向流的过渡.
- 低和振荡性透气性WSS被确定为血管疾病的潜在贡献者.
- 这些发现提供了对主动脉剖析和动脉样硬化的基础生物力学的见解.
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