在实体器官移植后,由传播的mycobacterium avium复合体疾病引起的肠道阻塞:一个病例报告
Akane Mita1, Sho Nakakubo2, Yusuke Nishimura3
1Department of Respiratory Medicine, Faculty of Medicine, Hokkaido University, North 15 West 7, Kita-ku, Sapporo, 060-8638, Japan.
BMC infectious diseases
|January 25, 2025
概括
传播的Mycobacterium avium复合体 (MAC) 感染是肝移植接受者的罕见并发症,模仿肠道恶性瘤. 早期诊断和警对于在免疫抑制患者中管理这些复杂病例至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 移植医学 移植医学
- 胃肠病学 胃肠病学
背景情况:
- 在免疫功能低下的个体中,Mycobacterium avium复合体 (MAC) 通常会导致肺部感染和传播疾病.
- 散布的MAC在实体器官移植接受者中不常见,这给诊断带来了挑战.
- 这一案例突出了肝移植后传播性MAC的罕见实例.
研究的目的:
- 在肝移植接受者中报告一种罕见的传播性Mycobacterium avium复合体 (MAC) 疾病病例.
- 强调在实体器官移植接受者中区分传播性MAC与恶性瘤的重要性.
- 要强调需要警的管理长期免疫抑制患者与非典型的感染.
主要方法:
- 一名76岁的肝移植接受者出现了暗示肠道阻塞的症状.
- 图像学研究 (CT,PET-CT) 和内镜检查显示了阻塞性肠道质量,最初怀疑是恶性淋巴瘤.
- 活检证实了通过识别酸快细菌传播的MAC感染.
主要成果:
- 散布的MAC感染呈现为阻塞性肠道质量,模仿肝移植接受者的恶性瘤.
- 患者需要长时间住院和干预胆汁排水和肠道营养尽管抗菌药物治疗.
- 活检的组织病理学检查对于准确的诊断至关重要.
结论:
- 应考虑在固体器官移植接受者呈现肠道阻塞的情况下传播MAC,即使是移植后的几年.
- 散布的MAC可以模仿恶性瘤,需要彻底的差异诊断.
- 管理非典型感染的免疫抑制患者的警对于及时和准确的患者管理至关重要.
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