在儿童感染COVID-19后评估长期肺功能:一个纵向观察队列研究
Muhammet F Korkmaz1, Gülsüm E Şenkan1, Şefika Elmas Bozdemir2
1Department of Pediatrics, University of Health Sciences, Bursa Faculty of Medicine, City Training and Research Hospital, Bursa, Turkey.
Journal of infection in developing countries
|January 26, 2025
概括
在2019年冠状病毒病 (COVID-19) 后对儿童的长期随访显示,中度和严重病例之间没有显著的肺功能差异. 肺功能测试 (PFTs) 显示了感染后大约15个月的类似结果.
科学领域:
- 儿科肺病学 儿科肺病学
- 传染性疾病 传染性疾病
- 呼吸系统药物 呼吸系统药物
背景情况:
- 评估COVID-19住院后儿童的长期肺功能变化.
- 根据疾病严重程度 (中度与严重) 调查潜在的差异.
研究的目的:
- 为了评估儿童COVID-19幸存者的肺功能结果.
- 为了在儿童中比较中度和严重的COVID-19病例之间的长期肺功能.
主要方法:
- 34名儿科患者 (7-18岁) 的前性纵向观察队列研究.
- 使用螺旋计进行的肺功能测试 (PFTs) 在感染后大约15个月进行.
- 在中度 (n=25) 和严重 (n=9) 的COVID-19组之间比较PFT结果.
主要成果:
- 在住院期间,严重程度组之间没有显著的人口,临床或结果差异.
- 总体而言,24%的儿童有异常的PFT (7%阻塞性,3%限制性).
- 在长期随访中,中度和重度COVID-19组之间的肺功能没有统计学上显著的差异 (p=0.105).
结论:
- 儿童COVID-19幸存者,无论最初的严重程度如何,都表现出类似的长期肺功能.
- 观察到的PFT异常 (阻塞/限制模式) 在中度和重度病例之间没有显著差异.
- 在这个队列中,持久的呼吸道症状与PFT差异没有相关性.
更多相关视频
相关概念视频
Lung Capacity
49.2K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
49.2K
Pulmonary Function Tests
292
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
292
Pulmonary Cycle: Exhalation
1.3K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.3K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K
Pulmonary Tuberculosis II
211
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
211
Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K


