在接受营养支持的患者中,低血症和死亡率之间的关系
Nayu Nakamura1, Arisa Inoue-Hamano1, Seiya Inoue2
1Department of Therapeutic Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, Japan.
Clinical nutrition (Edinburgh, Scotland)
|January 26, 2025
概括
接受营养支持小组 (NST) 干预的患者的持续性低血与显著更高的死亡风险有关. 即使是一次低血症也会增加死亡风险,强调需要对其进行管理.
科学领域:
- 临床医学 临床医学
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 低血是常见的,但往往无法管理,特别是轻微的病例.
- 新出现的证据将低血量,即使是轻微的,与死亡率的增加联系在一起.
- 接受营养支持团队 (NST) 干预的患者患低血的发病率更高.
研究的目的:
- 研究NST患者的低血发育/改善和死亡率之间的关联.
- 分析在NST干预前后基于低血状态的生存率.
主要方法:
- 对1553名接受初始NST干预的患者 (2013-2017年) 的回顾性分析.
- 根据血清水平分为四组:持续的低血症 (L-L),正常至低 (N-L),低至正常 (L-N) 和正常 (N-N).
- 5年生存率和死亡危险比率 (HR) 的计算,根据年龄,性别和BMI进行调整.
主要成果:
- 持续性低血症 (L-L) 显示死亡风险最高 (HR=3.47).
- 改善的低血症 (L-N) 的风险低于L-L,但与N-N相比仍然较高 (HR=2.19).
- 与N-N组 (HR=1.97) 相比,任何低血症发作 (L-N,N-L) 都会增加死亡风险.
结论:
- 低血症与接受NST的患者的生存率差显著相关.
- 纠正低血症可能会改善存活率,这需要进一步调查.
- 预防和管理NST患者的低血是至关重要的.
相关概念视频
Regulation of Water Intake
451
Osmolality refers to the number of solute particles per kilogram of solvent in a solution. Plasma osmolality specifically indicates the total number of solute particles per kilogram of water in blood plasma. This value reflects the body's hydration status and is tightly regulated through mechanisms controlling water intake and output. While water consumption is a conscious decision, the body has intrinsic regulatory systems to maintain fluid balance. Dehydration, a state of water deficit...
451
Disorder of Water Balance
278
Water balance disorders are medical conditions that occur when there is a deviation from the body's water volume or osmolarity, disrupting normal homeostasis and leading todehydration, hypotonic hydration, hyperhydration, edema, or water intoxication.
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
278
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
72
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
72
Tonicity in Animals
2.9K
Tonicity describes the amount of solute in a solution. The measure of the tonicity of a solution, or the total amount of solutes dissolved in a specific amount of solution, is called its osmolarity. Three terms—hypotonic, isotonic, and hypertonic—are used to relate the osmolarity of a cell to the osmolarity of the extracellular fluid that contains the cells. In a hypotonic solution, such as tap water, the extracellular fluid has a lower concentration of solutes than the fluid inside...
2.9K
Enteral Nutrition I: Orogastric and Nasogastric Feeding
189
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
189
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
96
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
96


