患有双相情感障碍和不患有双相情感障碍的自闭症青少年的睡眠障碍:一项匹配的病例对照研究
Busra Yıldız Bayındır1, Murat Coskun2, Ali Karayagmurlu2
1Council of Forensic Medicine, Ministry of Justice, İstanbul, Turkey.
Sleep medicine
|January 26, 2025
概括
睡眠障碍在自闭症青少年中更为普遍,特别是那些患有并发性双相情感障碍的青少年. 这些睡眠问题与自闭症谱系障碍 (ASD) 和双相情感障碍 (BD) 的行为问题增加有关.
科学领域:
- 神经发育障碍 神经发育障碍
- 精神病的并发症 精神病的并发症
- 睡眠医学 睡眠医学
背景情况:
- 在患有自闭症谱系障碍 (ASD) 和双相情感障碍 (BD) 的人群中,经常观察到睡眠障碍.
- 关于青少年患有自闭症的睡眠障碍的研究有限,特别是关于并发性BD的影响.
- 这项研究通过调查自闭症青少年的睡眠障碍,包括并发性BD,来弥补这一差距.
研究的目的:
- 确定自闭症青少年睡眠障碍的患病率和特征.
- 为了比较自闭症青年与并发性双相情绪障碍和那些没有情绪障碍的人之间的睡眠障碍.
- 在这个人群中探索睡眠障碍和行为问题之间的关联.
主要方法:
- 一项病例对照研究涉及43名患有ASD和BD的个体 (病例组) 和43名仅患有ASD的年龄/性别匹配个体 (对照组).
- 使用儿童睡眠障碍量表 (SDSC),儿童自闭症评分量表 (CARS) 和异常行为检查表 (ABC) 的评估.
主要成果:
- 病例组 (ASD与BD) 与对照组 (仅ASD) 相比,睡眠呼吸障碍,兴奋障碍,过度嗜睡和睡眠过症的发生率明显更高.
- 部分相关性分析表明,在两组中,SDSC总分数和ABC总分数之间存在显著的关联,这表明睡眠问题和行为问题之间存在联系.
- 睡眠障碍在自闭症青少年中更为常见,在伴随性双相情感障碍的存在下,患者的发病率进一步提高.
结论:
- 睡眠障碍在自闭症青少年中很常见,并因伴随性双相情感障碍而恶化.
- 睡眠问题与自闭症青少年的行为困难增加有关,无论伴随性情绪障碍.
- 睡眠障碍的常规评估和管理对自闭症青少年至关重要,特别是那些患有并发性情绪障碍的青少年.
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