患有子宫内膜异位症的不孕妇女在接受辅助生殖技术的生殖结果
Can Benlioglu1, Savci Bekir Telek2, Baris Ata1,3
1Department of Obstetrics and Gynecology, Koc University School of Medicine, Istanbul, Turkey.
Gynecologic and obstetric investigation
|January 26, 2025
概括
子宫内膜异位症本身不会影响辅助生殖技术 (ART) 的成功,除非卵巢储备受到损害. 目前的治疗方法并不能显著改善子宫内膜异位症患者的ART结果.
科学领域:
- 生殖医学 生殖医学
- 不孕症研究 不孕症研究
- 妇科 妇科 妇科 妇科
背景情况:
- 子宫内膜异位症是不孕症的常见原因,但其对辅助生殖技术 (ART) 结果的影响尚未完全理解.
- 炎症因素和诸如腺菌症之类的同时存在的疾病使得评估子宫内膜异位症对ART成功的直接影响变得复杂.
- 最近的数据质疑子宫内膜异位症对ART结果的影响程度,特别是在euploid转移和捐赠周期中.
研究的目的:
- 评估子宫内膜异位症对卵细胞能力的影响,ART成功率,以及手术或医疗干预的有效性.
- 综合目前关于子宫内膜异位症与ART各个阶段之间关系的证据.
主要方法:
- 专注于最近的高质量证据,包括系统审查,大规模观察研究和元分析.
- 综合数据提供了对子宫内膜异位症对ART的影响的强有力的理解.
主要成果:
- 卵子细胞产量可能会随着子宫内膜瘤的存在或切除史而降低,但卵子细胞质量,胚胎发育和阳积分率与其他不孕症诊断相比较.
- 在ART之前的手术治疗和激素抑制似乎没有改善结果.
- 对ART的卵巢刺激不会使子宫内膜异位症症状恶化.
结论:
- 子宫内膜异位症通常不会影响ART的成功,除非卵巢储备受到疾病或其治疗的影响.
- 子宫内膜异位症和不孕不育之间的直接因果关系尚不清楚,需要进一步研究混因素.
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