Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

2.4K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.4K
Regression Toward the Mean01:52

Regression Toward the Mean

6.3K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.3K
Correlation between ECG and Cardiac Cycle01:25

Correlation between ECG and Cardiac Cycle

3.3K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
3.3K
Regulation of Heart Rates01:31

Regulation of Heart Rates

1.6K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
1.6K
Pathophysiology of Cardiac Performance01:29

Pathophysiology of Cardiac Performance

517
Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
517
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

142
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
142

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Single-cell analysis reveals IL1B<sup>+</sup> macrophages promote lung metastasis in adenoid cystic carcinoma.

Cancer letters·2026
Same author

Plant-Derived Exosome-Like Nanoparticles: Mechanisms of Cross-Kingdom Regulation and Perspectives as Natural Drug Carriers for Disease Treatment.

International journal of nanomedicine·2026
Same author

[<i>Huangqin Qingre Chubi</i> Capsule inhibits JAK/STAT-driven synovial angiogenesis in rheumatoid arthritis by suppressing the LncRNA EBLN3P/miR-369-3p/NFIX axis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University·2026
Same author

HOXD13-mediated immune crosstalk between cancer cells and tumor-associated macrophages drives colorectal cancer progression.

Journal for immunotherapy of cancer·2026
Same author

Isolation and Identification of Endophytic <i>Chaetomium</i> sp. Strain V3 from <i>Ambrosia</i> and Its Effects on Tomato Plant Growth.

Journal of fungi (Basel, Switzerland)·2025
Same author

Cichoric acid-loaded hydroxyapatite nanorods remodel the immune microenvironment to enhance bone regeneration.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2025

相关实验视频

Updated: May 30, 2025

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
08:12

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

19.8K

心率变化特征与中风之间的关系:孟德尔的随机化研究.

Wei Liu1, Yexin Xin2, Mengyu Sun2

  • 1Shandong First Medical University, Jinan, Shandong 250117, China; Department of Neurosurgery, Liaocheng People's Hospital, Liaocheng, Shangdong 252000, China.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
|January 26, 2025
PubMed
概括

这项研究使用了门德尔的随机化来研究心率变化 (HRV) 和中风之间的因果关系. 遗传证据支持某些HRV措施因果关系地影响缺血和大动脉中风风险.

关键词:
因果关系是因果关系.心率变化心率的变化.缺血性中风是因为缺血性中风.大动脉中风的大动脉中风门德尔的随机化

更多相关视频

Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis
08:22

Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis

Published on: April 26, 2024

1.7K
Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

1.7K

相关实验视频

Last Updated: May 30, 2025

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions
08:12

Calculating Heart Rate Variability from ECG Data from Youth with Cerebral Palsy During Active Video Game Sessions

Published on: June 5, 2019

19.8K
Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis
08:22

Author Spotlight: Advancing the Study of Brain-Heart Interplay with a Comprehensive EEGLAB Plugin for Multimodal Signal Analysis

Published on: April 26, 2024

1.7K
Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
05:32

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model

Published on: August 11, 2023

1.7K

科学领域:

  • 心血管流行病学心血管流行病学
  • 遗传学 是一个遗传学.
  • 神经学 神经学

背景情况:

  • 观察性研究表明,心率变化 (HRV) 和脑血管疾病之间存在联系.
  • HRV和中风之间的因果关系还没有最终确定.

研究的目的:

  • 用两个样本的孟德尔随机化分析来调查HRV和中风之间的因果关系.
  • 探索特定HRV测量和各种中风亚型之间的潜在因果关系.

主要方法:

  • 利用了HRV特征 (SDNN,RMSSD,pvRSA/HF) 和中风亚型 (IS,LAS,LS等) 的全基因组关联研究数据. ) 的情况.
  • 采用双样本门德尔随机化与反变量加权 (IVW) 作为主要方法.
  • 进行了敏感性分析,包括Cochran的Q测试,MR-Egger的拦截,MR-PRESSO和留出一个方法,以确保结果的可靠性.

主要成果:

  • 心率变化 (SDNN) 显示与缺血性中风 (IS) 和大动脉中风 (LAS) 的因果关系.
  • 峰谷呼吸节律失常/高频电源 (pvRSA/HF) 与IS,LAS和性中风 (LS) 有因果关系.
  • 连续差异的平方根平均值 (RMSSD) 与任何中风亚型没有显著的关联.

结论:

  • 为HRV (SDNN) 对IS和LAS的因果作用提供遗传证据.
  • 表明HRV (pvRSA/HF) 在IS,LAS和LS中起因作用.
  • 突出了特定的HRV指标作为不同类型中风的潜在因果因素.