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Chao-Fan He¹, Ye Yang¹, Yong Liu¹

¹Fuyang Normal University-Funan Rural Revitalization Collaborative Technology Service Center, Fuyang Normal University, Fuyang, 236041, People's Republic of China.

Fish & shellfish immunology

|January 26, 2025

概括

细菌细菌,特别是表达的重组形式,改善了中国大白的生长和对细菌毒素的抵抗力. 这支持使用植物性料添加剂来促进更健康的水产养殖和减少抗生素的使用.

科学领域:

水产养殖是水产养殖的一种方式.
甲动物生物学甲动物生物学
免疫学免疫学免疫学

背景情况:

中国手套 (Eriocheir sinensis) 水产养殖至关重要,但由于有限的适应性免疫系统,压力耐受性较差而受到阻碍.
来自细菌的脂聚糖 (LPS) 会在中引起显著的氧化应激和肝胰腺损伤.
从棉花中先前发现的一种 (cmP4) 在体外显示出抗氧化和增强免疫力的特性.

研究的目的:

为了评估补充细菌素 (未经修改和重组) 的饮食对中国大白生长的影响.
评估这些饮食对LPS诱导的急性氧化应激和肝胰腺损伤的保护作用.
为了比较复合B. subtilis表达一个协同 (cmP4') 与未经修改的B. subtilis的疗效.

主要方法:

被养了12周的基础,B. subtilis补充或重组B. subtilis补充饮食.
进行LPS挑战,以评估抗氧化能力,氧化应激指数,线粒体膜潜力和亡.
进行了肝胰腺组织病理学分析.

主要成果:

这两种B. subtilis饮食都改善了的生长性能.
B. subtilis补充剂增强了抗氧化能力,并减少了氧化应激和LPS挑战后的肝胰腺损伤.
再组合B. subtilis与未经修改的B. subtilis相比,表现出更好的保护作用,测量指数的改善更大.

结论:

细菌细菌,特别是复合形式,有效地增强了中国的生长和应激耐受性.
这项研究支持在水产料中使用植物蛋白副产品和微生物添加剂.
这些发现促进了对E. sinensis.的无抗菌水产养殖实践.

关键词:

甲动物培养养殖肝脏损伤损伤的损伤脂聚糖类糖化物脂聚糖类糖化物氧化应激是一种氧化应激.再组合的细菌subtilis的细菌.

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