对于绿地对宏观体的影响和与空气污染物相互作用的敏感月份:出生队列研究
Dongshuai Wang1, Yajuan Zhang1, Xuehao Dong1
1School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, 750004, China.
Environmental pollution (Barking, Essex : 1987)
|January 26, 2025
概括
在怀孕晚期,特别是第九个月,增加绿色空间的暴露显著降低了胎儿宏观症的风险. 当与减少对二氧化和二氧化硫等空气污染物的暴露相结合时,这种益处会得到放大.
科学领域:
- 环境流行病学环境流行病学
- 孕产妇和儿童的健康
- 公共卫生 公共卫生
背景情况:
- 麦克罗索米亚对母亲和胎儿都有很大的健康风险.
- 怀孕期间的关键发育时期 (敏感窗口) 对绿色空间暴露对宏观风险的影响还不清楚.
- 绿色空间的可用性和空气污染物暴露之间的相互作用需要进一步调查.
研究的目的:
- 为了确定在怀孕期间对绿色空间暴露的敏感窗口,这些窗口会影响宏观症的风险.
- 研究绿色空间资源和空气污染物对宏观生物的综合影响.
- 为了分析这些协会之间的差异,宏观症 (<4500克) 和严重的宏观症 (≥4500克) 组.
主要方法:
- 在宁夏地区对221,380名满期新生儿 (2017-2021) 进行了一项大型队列研究.
- 规范差异植被指数 (NDVI) 和空气污染物数据 (NO2,SO2) 被地理定位到参与者的住所.
- 考克斯的比例危险模型和相互作用分析被用来评估不同缓冲区 (250-2000米) 的关联和敏感窗口.
主要成果:
- 在整个怀孕期间,更大的绿色空间暴露 (更高的NDVI) 与较低的宏观症风险有关,特别是在严重的宏观症组中.
- 绿色空间的最显著的保护作用是在怀孕晚期观察到的,特别是第九个月.
- 在有限的绿色空间和高水平的空气污染物 (NO2和SO2) 之间发现了联合有害影响.
结论:
- 在怀孕晚期增加绿色空间的可用性提供了对宏观的保护作用.
- 公共卫生战略应考虑绿色空间和空气污染对胎儿生长的协同影响.
- 促进绿色空间的城市规划和环境政策可以有助于减轻宏观风险.
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