在日本,从肉中发现抗菌素耐药性沙门氏菌的地理差异
Yoshimasa Sasaki1, Yoko Furuya2, Shotaro Suzuki1
1Division of Veterinary Science, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
The Journal of veterinary medical science
|January 26, 2025
概括
日本肉中的沙门氏菌对抗菌素的耐药性因地区而异. 发现了对常见抗生素的高耐药率,特别是在九州,影响了食品安全战略.
科学领域:
- 食品微生物学 食品微生物学
- 抗微生物耐药性 抗微生物耐药性
- 兽医公共卫生 兽医公共卫生
背景情况:
- 在全球范围内,肉是食源性沙门氏菌病的重要来源.
- 在日本,沙门氏菌胃肠炎的治疗依赖于化诺和第三代化素.
- 了解食品传播病原体中抗菌素耐药性模式对于公共卫生至关重要.
研究的目的:
- 确定日本不同地区肉产品中沙门氏菌的流行率和抗菌耐药性.
- 为了识别特定的沙门氏菌血清病毒及其耐药性概况.
- 评估抗微生物药物耐药性的地理差异.
主要方法:
- 在日本北海道,东北,関東和九州收集的154个肉样本中隔离和识别沙门氏菌.
- 单独的沙门氏菌菌株对各种抗生素的抗菌感应性测试.
- 对沙门氏菌血清菌的流行和区域性耐药性模式的分析,重点关注沙门氏菌.
主要成果:
- 在86.4% (133/154) 的肉产品中检测到沙门氏菌.
- 观察到高耐药率的链杆菌素 (56.5%),四环素 (50.7%),和卡纳米素 (47.8%).
- 所有的分离物仍然对塞法林,塞福他西姆, جنت米辛,西普罗夫洛克萨,胆素和氨基醇敏感.
- 沙门氏菌是占主导地位的血清菌 (83.3%),并且在多药耐药性方面表现出显著的区域差异 (100%在九州,41.5%在东北,0%在北海道).
结论:
- 在日本的肉中,沙门氏菌,特别是沙门氏菌的抗菌耐药性存在显著的地理差异.
- 在九州,抗药性沙门氏菌在九州的高患病率要求注意食品安全和公共卫生干预措施.
- 对临床关键抗生素 (如西普罗夫洛克萨和第三代胞) 的敏感性提供了治疗选择,但区域性耐药性监测至关重要.
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