创伤性脑损伤后的睡眠和昼夜节律
Narges Kalantari1, Nadia Gosselin1
1Department of Psychology, Université de Montréal, Montreal, QC, Canada; Center for Advanced Research in Sleep Medicine, Hôpital du Sacré-Cœur de Montréal, Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de Montréal, Montreal, QC, Canada.
Handbook of clinical neurology
|January 26, 2025
概括
创伤性脑损伤 (TBI) 显著影响睡眠,导致失眠和过度白天嗜睡等问题. 个性化治疗方法对于改善TBI患者的睡眠和恢复至关重要.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 创伤性脑损伤 (TBI) 是年轻人死亡和残疾的主要原因.
- 睡眠-觉醒障碍影响50-70%的TBI患者,无论伤害严重程度如何,都会持续存在.
- 这些障碍包括过度的白天嗜睡,疲劳,高睡眠和失眠,通常与疼痛,焦虑和抑郁有关.
研究的目的:
- 审查TBI后持续的睡眠和清醒障碍.
- 探索睡眠架构变化之外的促成因素,包括昼夜系统变化.
- 总结TBI后睡眠障碍的当前和建议的治疗策略.
主要方法:
- 对TBI和睡眠-觉醒障碍研究的文献综述.
- 分析报告的睡眠变化,相关症状和治疗疗效.
- 综合了关于昼夜节律扰乱作用的研究结果.
主要成果:
- 睡眠-觉醒障碍是TBI的常见和使人虚弱的后果.
- 虽然睡眠架构发生了变化,但昼夜计时系统的改变也起到了重要作用.
- 现有的治疗方法,如CBT,睡眠卫生,光疗和药物干预,显示出有前途.
结论:
- 睡眠障碍严重影响创伤后的康复,认知功能和社区融合.
- 由于TBI后果的异质性,个性化治疗计划是必不可少的.
- 优先考虑早期查和量身定制的干预措施可以改善睡眠并加速TBI幸存者的康复.
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