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Updated: May 30, 2025

An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity
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An In Vitro Assay to Detect tRNA-Isopentenyl Transferase Activity

Published on: October 8, 2018

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通过Induro-tRNAseq对tRNA修饰的全基因组分析显示了协调的变化

Yuko Nakano1, Howard Gamper1, Henri McGuigan1

  • 1Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA, USA.

Nature communications
|January 26, 2025
PubMed
概括

这项研究介绍了Induro-tRNAseq,一种使用Induro逆转录酶 (RT) 绘制全基因组tRNA修改图的新方法. 它克服了阅读修改后的tRNA的挑战,揭示了蛋白质平衡所必需的稳定修改模式.

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