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测量金属的方法:从ICP-MS到XRF

Kolawole E Adesina¹, Chandler J Burgos¹, Thomas R Grier¹

¹School of Health Sciences, Purdue University, West-Lafayette, IN, 47906, USA.

Current environmental health reports

|January 26, 2025

概括

感应合等离子体质谱 (ICP-MS) 和X射线光 (XRF) 提供了在生物样本中先进的金属量化. ICP-MS为实验室分析提供了高灵敏度,而XRF允许快速实地测试,为各种研究需求指导方法选择.

科学领域:

分析化学分析化学
环境科学环境科学
生物医学科学生物医学科学

背景情况:

金属和金属化物在生物系统和环境健康中起着至关重要的作用.
在复杂的生物矩阵中精确量化这些元素对于诊断和研究至关重要.
感应合等离子体质谱 (ICP-MS) 和X射线光 (XRF) 是元素分析的关键分析技术.

研究的目的:

审查和比较诱导合等离子体质谱 (ICP-MS) 和X射线光 (XRF) 用于生物样本中的金属和金属化物量化.
详细介绍ICP-MS和XRF的技术能力,局限性和应用范围.
引导研究人员和临床医生根据灵敏度,精度,速度和样本准备要求选择最佳分析方法.

主要方法:

对生物矩阵中ICP-MS和XRF应用的现有文献进行全面审查.
分析技术进步,包括灵敏度,检测极限和速度.
对实验室和实地分析的实际考虑的评估.

主要成果:

在复杂的生物样本中,ICP-MS在超微金属检测方面表现出卓越的灵敏度和精度.
XRF提供快速,非破坏性分析,检测极限较低,非常适合现场评估和快速选.
新兴的混合技术和便携式XRF分析仪提高了多功能性和现场能力.
方法的选择取决于样本的复杂性,所需的灵敏度,速度和成本效益.

结论:

ICP-MS和XRF都是生物样本中金属和金属化物分析的强大工具,每个都有不同的强度.
ICP-MS是用于高精度,敏感量化的实验室标准.
在快速,非破坏性和现场部署的分析中,XRF卓越.
整合这些技术为环境监测,临床诊断和健康研究提供了一种多功能方法.

关键词:

生物样本生物样本这些元素元素.在ICP-MS中,使用的是ICP-MS.金属金属金属量化量化量化量化频谱测量是一种光谱测量.这是XRFXRF.

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