习惯性睡眠时间,健康饮食,以及消化系统癌症死亡率
Diana A Nôga1, Elisa M S Meth2, André P Pacheco2,3,4
1Department of Pharmaceutical Biosciences, Uppsala University, Box 593, Husargatan 3, Uppsala, 751 24, Sweden. diana.noga.morais@uu.se.
BMC medicine
|January 26, 2025
概括
短时间和长时间的睡眠时间都与更高的消化系统癌症死亡风险有关. 健康的饮食可能会提供保护,但这种效果不会因睡眠模式而减少. 需要进一步的研究.
科学领域:
- 消化系统的健康状况
- 癌症流行病学癌症流行病学
- 睡眠科学 睡眠科学
背景情况:
- 饮食和睡眠等生活方式因素显著影响消化系统的健康.
- 这些因素可能会在由消化系统癌症导致的死亡风险中发挥作用.
研究的目的:
- 调查睡眠时间,饮食习惯和由消化系统癌症引起的死亡率之间的联系.
- 分析来自大型队列的数据,以了解这些关系.
主要方法:
- 利用了来自406,584名参与者 (38-73岁) 的英国生物库数据.
- 睡眠时间分为短 (≤6h),正常 (7-8h) 和长 (≥9h).
- 评估饮食习惯,使用基于纤维,水果/蔬菜和肉类摄入量的得分;采用Cox比例危险回归,随访12.6年.
主要成果:
- 短时间和长时间的睡眠时间与消化系统癌症死亡风险增加有关.
- 健康饮食得分 (≥1) 与消化系统癌症死亡率降低的风险有关.
- 在调整吸烟,2型糖尿病和BMI后,睡眠时间和死亡率之间的关联被排除;健康饮食的保护作用独立于睡眠时间.
结论:
- 异常的睡眠时间可能会增加消化系统癌症的死亡风险,这可能是由吸烟,BMI和2型糖尿病引起的.
- 健康的饮食模式似乎保留了它们对消化癌死亡率的保护作用,无论睡眠时间如何.
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