阻塞性睡眠呼吸暂停和结构性和功能性大脑变化:从临床关联到遗传因果关系的全脑调查

Kang Wu1, Qiming Gan1, Yuhong Pi1

  • 1Sleep Medicine Center, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, NO.28 Qiaozhong Mid Road, Guangzhou, Guangdong, 510160, China.

BMC medicine
|January 26, 2025
PubMed
概括

阻塞性睡眠呼吸暂停 (OSA) 与大脑变化有关,特别是在额叶. 这项研究使用MRI和遗传数据表明缺氧诱导的神经损伤和神经元失衡有助于OSA相关的大脑变化.