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Updated: May 30, 2025

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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Published on: January 16, 2016

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祖先序列重建和全面的计算模拟揭示了一个高效的PET水解酶与摇摆的催化三合一

Yibo Song1, Anni Li1, Haiyang Cui2,3,4

  • 1School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210009, People's Republic of China.

ChemSusChem
|January 27, 2025
PubMed
概括

祖先序列重建 (ASR) 设计了一种新型的PET酶,ASR1-PETase,可以有效降解聚乙烯四甲酸盐 (PET). 这种酶利用独特的氨酸催化部位来增强PET水解和TPA生产.

关键词:
祖先序列重建 (ASR) 是一种方法.微秒级分子动力学模拟.在PET生物降解过程中.酸酶 (PETase) 是一种质量管理集群计算 QM集群计算

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