睡眠持续时间,睡眠障碍和骨肌肉质量随时间变化:秘鲁基于人口的纵向分析
Renzo A Agurto-García1, Enrique S Nuñez-Del-Arco1, Rodrigo M Carrillo-Larco2,3
1Universidad Cientifica del Sur, Lima, Peru.
Wellcome open research
|January 27, 2025
概括
睡眠障碍与随着时间的推移而减少的骨肌肉质量 (SMM) 有关. 虽然短睡者没有显示任何变化,但长睡者经历了SMM减少,特别是通过生物阻抗测量时.
科学领域:
- 老年学是一门学科.
- 代谢过程中的代谢.
- 睡眠科学 睡眠科学
背景情况:
- 骨肌肉质量 (SMM) 对新陈代谢和结构至关重要.
- 肉症,或肌肉质量下降,与睡眠质量差有关.
- 这项研究调查了秘鲁成年人的睡眠模式和SMM变化之间的关系.
研究的目的:
- 为了确定随着时间的推移,骨肌肉质量的变化是否与基线睡眠时间有关.
- 评估睡眠障碍与骨肌肉质量变化之间的关联.
- 在资源有限的秘鲁成年人口中分析这些关系.
主要方法:
- 基于人口的干预数据集的二次分析.
- 通过生物阻抗和李公式评估的骨肌肉质量 (SMM).
- 记录了基线睡眠时间 (正常,短,长) 和睡眠障碍 (困难,夜间醒来).
- 线性混合模型分析了关联,报告系数 (β) 和95%置信区间 (95% CI).
主要成果:
- 分析包括2310名成年人 (平均年龄为43.4岁,女性为50.4%).
- 使用李的公式,短睡眠和长睡眠的人没有随着时间的推移显著的SMM变化.
- 长睡眠者表现出降低的SMM与生物阻抗 (-0.26公斤).
- 睡眠障碍与SMM逐渐减少相关 (0.36公斤生物阻抗,0.25公斤李公式).
结论:
- 睡眠障碍与骨肌肉质量 (SMM) 在2.4年内减少有关.
- 在短睡者中没有观察到SMM变化.
- 对于长时间睡眠的人来说,生物阻抗和李的公式之间存在不一致的发现,这表明在SMM评估上可能存在依赖方法的影响.
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