对神经病患者维生素D状况的回顾性观察性研究
Lucija Zadro Matovina1,2, Helena Trputac1, Antonia Nicinger3
1Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.
Acta clinica Croatica
|January 27, 2025
概括
神经病患者的维生素D缺乏率很高,但略低于克罗地亚一般人口. 补充剂和自身免疫性疾病的诊断显著影响维生素D水平.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 维生素D缺乏是一个日益严重的全球健康问题.
- 神经疾病可能与维生素D代谢的改变有关.
- 了解神经病患者的维生素D状况对于管理至关重要.
研究的目的:
- 确定克罗地亚神经病患者中维生素D缺乏症的患病率.
- 为了将这种患病率与克罗地亚一般人口进行比较.
- 探索影响维生素D不足的因素,包括补充剂和自身免疫性疾病.
主要方法:
- 在一年内对371名神经病患者进行了回顾性分析.
- 收集的数据:人口统计,神经诊断,血清25-氧维生素D水平和维生素D3补充史.
- 跨子组的维生素D缺乏率的统计比较.
主要成果:
- 74.66%的神经病患者表现出维生素D缺乏 (<75nmol/L).
- 这种患病率略低于克罗地亚一般人口.
- 维生素D缺乏症根据维生素D3补充剂和自身免疫性疾病诊断有显著的变化,但不是性别,季节或地区.
结论:
- 大部分神经病患者患有维生素D缺乏症.
- 维生素D补充剂和自身免疫性疾病的存在是影响这些患者维生素D状况的关键因素.
- 对神经病患者的向维生素D干预措施的进一步研究是有必要的.
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