生物牙的3D打印具有多个有序的等级结构
Menglu Zhao1, Yanan Geng1, Suna Fan1
1State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.
Materials today. Bio
|January 27, 2025
概括
研究人员开发了一种新的3D打印方法,以模仿天然牙结构. 这种技术精确地控制酸 (HAp) 纳米结构的方向,创造了具有增强生物相容性的先进牙冠.
科学领域:
- 生物材料工程 生物材料工程
- 纳米技术 纳米技术
- 牙科材料科学 牙科材料科学
背景情况:
- 自然牙呈现出复杂的组成异质性和酸盐 (HAp) 纳米结构,位于牙和牙之间.
- 在人工牙科材料中复制这种复杂的自然微观结构仍然是一个重大挑战.
研究的目的:
- 开发一种新的多材料牙冠的制造方法,模仿自然牙的异质微观结构.
- 为了实现精确控制酸 (HAp) 纳米结构在牙面膜结 (DEJ) 的方向.
主要方法:
- 采用了一种自下而上的顺序方法,将剪切诱导和磁辅助3D打印技术结合起来.
- 酸 (HAp) 纳米棒通过剪切力和磁场定向,在牙和牙层中创建特定的结构.
- 这些材料被3D打印成一个双层牙冠,具有特定位置的组成和纹理.
主要成果:
- 制造一种具有高度秩序的HAp纳米结构的多材料牙冠,几乎垂直于DEJ.
- 3D打印的皇冠展示了特定地点的组成和纹理,密切模仿天然牙结构.
- 制造的材料显示出出色的生物相容性.
结论:
- 开发的剪切诱导和磁辅助3D打印方法使牙科修复的精确多层次和多维纹理控制成为可能.
- 这种新的技术显示出了设计和制造人工牙冠的巨大潜力,可以复制自然牙的异质性和功能.
相关概念视频
01:55Bone Structure
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
01:15Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
01:21Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
01:28Three-Dimensional Microscopy in Microbiology
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...