除了甜点之外的鞭子:引起亚急性综合退化 - 案例报告和文献综述
Vijayalakshmi Brahmashettar1, Elton Ahadov2, Tamilla Rzayeva2
1Department of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
Journal of community hospital internal medicine perspectives
|January 27, 2025
概括
娱乐性氧化 (N2O) 的使用可以通过耗尽维生素B12而导致严重的神经损伤. 早期诊断和治疗对于防止这种受欢迎的吸入剂造成永久性神经损伤至关重要.
科学领域:
- 神经学 神经学
- 毒理学 毒理学 毒理学
- 营养科学 营养科学
背景情况:
- 娱乐性氧化 (N2O) 的使用正在增加,导致其与神经系统缺陷有关.
- N2O使维生素B12失活,这是神经功能的一个关键辅因子.
- 目前针对N2O诱导的神经损伤的治疗方法存在局限性,有可能导致永久性后果.
研究的目的:
- 呈现一个副急性综合性退化 (SCD) 病例,其次是娱乐性N2O滥用.
- 为了强调与吸入药物滥用相关的神经并发症.
- 强调在患有无法解释的神经症状的患者中考虑N2O毒性的重要性.
主要方法:
- 一个50岁的女性的病例报告显示,她有失衡,认知能力下降,跌倒和背部疼痛等症状.
- 临床评估,包括体检和脊椎磁共振成像 (MRI).
- 通过患者病史和附带信息识别娱乐性N2O滥用.
主要成果:
- 患者呈现出符合亚急性综合性退行症 (SCD) 的症状.
- 磁力共振成像证实了部和胸部脊柱的SCD.
- 诊断与娱乐性使用氧化有关,通常称为"鞭打它! ". ". 这就是为什么.
- 对维生素B缺乏进行了适当的治疗.
结论:
- 娱乐性氧化使用存在严重和可能永久的神经损伤的重大风险.
- 亚急性综合性退行症是慢性N2O滥用的关键神经学表现.
- 提高意识和及时诊断对于管理N2O诱导的神经毒性至关重要.
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