付款前策略减少了HPV疫苗的延迟,并增加了追赶年龄的女孩的接种率:一个随机临床试验
Jing Li1, Yifan Li2, Chuanyu Qi1
1West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
medRxiv : the preprint server for health sciences
|January 27, 2025
概括
支付前付策略显著增加了中国青少年女孩的人类乳头瘤病毒 (HPV) 疫苗接种率. 这种创新方法被证明比标准护理更具成本效益,用于追赶HPV免疫.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 卫生经济学 卫生经济学
背景情况:
- 赶上人类乳头瘤病毒 (HPV) 疫苗接种在低收入和中等收入国家 (LMICs) 提出了挑战.
- "付前付"模式补贴一个人的疫苗,并允许他们为其他人捐赠.
- 这项研究评估了中国青少年女孩的HPV疫苗接种支付前付策略.
研究的目的:
- 评估支付前付策略在促进HPV疫苗接种方面的有效性.
- 为了比较支付前付与标准自付疫苗接种的成本效益.
- 评估参与者和护理人员愿意参与模型的捐赠方面.
主要方法:
- 一项随机对照试验在中国对15-18岁的女孩进行.
- 参与者被分配到支付前期支付或标准护理 (自付) 部门.
- 主要结局是通过临床记录验证的第一剂HPV疫苗接种率.
主要成果:
- 与标准护理 (17.5%) 相比,支付前期治疗组的第一剂HPV疫苗接种率 (34.2%) 显著更高.
- 调整后的比例差异有利于前期付款组 (17.9%,P<0.001).
- 接种疫苗的人均费用在支付前期手臂 (230美元) 与标准护理 (294美元) 相比较低.
结论:
- 亲社会支付前付策略有效地增加了青少年女孩的HPV疫苗接种.
- 该模型显示了可比或改进的成本效益.
- 在付前付的部门中,在明信片消息和护理人员捐款中观察到高参与度.
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