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Updated: Jun 14, 2026

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

使用Link-Seq对人类B细胞谱的可变抗体域和个体转录组进行有针对性的条形码化

Hongxing Hu1,2, Fan Zhou3, Xiaoli Ma1

  • 1Institute of Bioengineering, School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

PNAS nexus
|January 27, 2025
PubMed
概括

链接-Seq是一种新的微流体方法,用于测序抗体基因和B细胞转录组. 这种技术在对抗体链的配对中实现了高精度,并为单细胞分析节省了成本.

关键词:
在RNA-seqqq.这是一种SARS-CoV-2感染.滴滴微流体学 滴滴微流体学免疫谱的测序 immune repertoire 的测序.一个单细胞分析.

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相关概念视频

RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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