来自NHANES的不规则脉和心血管疾病 (1999-2018):一个横截面研究
Qingping Zeng1, Weihong Chang1, Rui Zhang1
1Department of Cardiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine Tsinghua University Beijing China.
Health science reports
|January 27, 2025
概括
不规律的脉与心血管疾病 (CVD) 和死亡率的更高风险有关. 这一发现强调了监测脉冲规律对于心血管疾病查和风险管理的重要性.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 不规则的脉是常规健康检查期间容易检测到的迹象.
- 关于脉不规律,心血管疾病 (CVD) 和死亡率之间的关联的大规模人口数据是有限的.
- 调查不规则脉作为潜在的心血管疾病查指标对于公共卫生政策至关重要.
研究的目的:
- 调查脉冲不规律与患心血管疾病 (CVD) 的风险之间的关联.
- 检查脉冲不规则与全因和心血管疾病特异性死亡率之间的关系.
- 探索不规则脉作为心血管疾病和死亡风险查工具的有用性.
主要方法:
- 一项大型队列研究利用了1999年至2018年国家健康和营养检查调查 (NHANES) 的数据.
- 包括49,681名具有有效心血管疾病和脉特征数据的成年参与者.
- 与到2019年的死亡率数据进行链接,以评估所有原因和心血管疾病死亡率的结果.
主要成果:
- 脉冲不规则的参与者显示心血管疾病的风险显著增加 (OR 1.34,95% CI [1.14,1.58]),包括心力衰竭 (OR 1.75,95% CI [1.37,2.24]) 和冠心病 (OR 1.27,95% CI [1.01,1.60]).
- 不规则的脉与所有原因死亡率 (HR 1.29,95% CI [1.17,1.42]) 和心血管疾病死亡率 (HR 1.53,95% CI [1.30,1.81]) 的更高风险有关.
- 在不规则脉组中,观察到所有原因死亡率 (p < 0.001) 和心血管疾病死亡率 (p < 0.001) 的统计学意义.
结论:
- 不规律的脉显著与心血管疾病和死亡率的增加有关.
- 这些发现强调了不规则脉冲检测在心血管风险评估中的重要性.
- 建议对有不规则脉的人进行定期健康查和积极的风险管理.
相关概念视频
01:05Pulse
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls between...
01:20Regulation of Pulse
Pulse regulation involves physiological mechanisms that ensure adequate blood flow throughout the body. The heartbeat, regulated by the autonomic nervous system, is influenced by hormonal balance, physical activity, and emotional state.
01:17Pulse amplitude and quality
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
01:30Pulse rhythm
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
01:13Special considerations while measuring pulse
Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
01:16Pulse
When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...
The pulse serves as a clinical indicator...