罕见的上皮性胃癌:对当前治疗知识的综述
Angelica Petrillo1, Margaret Ottaviano2, Luca Pompella3
1Medical Oncology Unit, Ospedale del Mare, Via E. Russo, Naples 80147, Italy.
这篇评论强调了解罕见的胃癌 (GCs) 以进行个性化治疗. 它旨在将稀缺的证据纳入临床实践,促进对这些罕见瘤的试验和合作.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
背景情况:
- 胃癌 (GC) 是全球癌症死亡的主要原因.
- GC是一种异质性疾病,具有不同的位置,宏观特征,基因型和分子变化.
- 罕见的上皮性GC占病例的5%,发病率低于每10万人/年的6,需要进一步阐明.
研究的目的:
- 突出了解个性化医学的罕见GC的重要性.
- 将罕见GCs的有限文献证据转化为临床实践.
- 鼓励患者参加临床试验和国际合作,为罕见的GCs.
主要方法:
- 这是一个叙事评论.
- 专注于将稀缺的证据转化为日常临床实践.
- 强调了解罕见的GCs的重要性.
主要成果:
- 罕见的GC,包括特定的腺癌,状细胞癌,状腺癌,神经内分泌瘤和胃母细胞瘤,需要量身定制的治疗策略.
- 个性化医疗方法对于优化罕见的GC病例的结果至关重要.
- 有限的证据需要专注于临床试验和协作努力.
结论:
- 对罕见的胃癌有更深入的了解,对于在瘤学中推进精准医学至关重要.
- 将现有证据整合到临床实践中,并通过试验和合作促进研究,是改善罕见GC患者治疗结果的关键.
- 该审查涵盖了特定罕见的胃腺癌,状细胞癌,状腺癌,神经内分泌新生体和胃母细胞瘤的治疗.
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