,IFN-γALPK1/TIFA

Amandine Martin1, Solène Caron1, Mélissa Marcotte1

  • 1CIRI, Centre International de Recherche en Infectiologie, Inserm U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, University Lyon, F-69007 Lyon, France.

iScience
|January 27, 2025
PubMed
概括

干扰素- (IFN-γ) 对于激活单细胞中的α-激酶1 (ALPK1) 途径至关重要,这与自身炎症性疾病有关. 雅克抑制剂可以治疗这些与ALPK1相关的炎症状况.

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