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Updated: May 30, 2025

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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通过 Cdk1/Wee1 信号电路进行 RPA 代码启动和调整的机制

Poonam Roshan, Vikas Kaushik, Ayush Mistry

    bioRxiv : the preprint server for biology
    |January 27, 2025
    PubMed
    概括

    在RPA70上的Cdk1对复制蛋白A (RPA) 的酸化对细胞循环和DNA修复至关重要. 这种原始化修改增强了RPA32的高酸化,揭示了DNA损伤反应必不可少的反循环.

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