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Updated: May 30, 2025

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
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Published on: April 23, 2016

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识别所需的最小的Alu域,以进行反转换

John B Moldovan1, John Yin1, John V Moran1,2

  • 1Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

bioRxiv : the preprint server for biology
|January 27, 2025
PubMed
概括

在Alu RNA的5'端有一个小的46核酸区,对于其逆转换至关重要,使其能够劫持LINE-1蛋白质. 这一发现澄清了灵长类动物特异性逆转移素调动的机制.

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