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Updated: May 30, 2025

Flow Cytometric Analysis of Mitochondrial Reactive Oxygen Species in Murine Hematopoietic Stem and Progenitor Cells and MLL-AF9 Driven Leukemia
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在Myc驱动的淋巴瘤中,PRPS活动调整了还氧化稳态

Austin C MacMillan1, Bibek Karki1, Juechen Yang2,3

  • 1Department of Cancer Biology, University of Cincinnati College of Medicine; Cincinnati, OH 45267, USA.

bioRxiv : the preprint server for biology
|January 27, 2025
PubMed
概括

Myc通过改变细胞代谢和氧化还原平衡来驱动淋巴瘤. 准PRPS酶为MYC驱动的淋巴瘤提供了一种新的治疗策略,通过调节细胞的氧化还原状态.

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