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Updated: May 30, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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AR-V7凝聚剂驱动了化抵抗性前列腺癌中的雄激素独立转录

Shabnam Massah, Nicholas Pinette, Jane Foo

    bioRxiv : the preprint server for biology
    |January 27, 2025
    PubMed
    概括

    雄激素受体变体7 (AR-V7) 在前列腺癌中形成核凝聚物,驱动瘤性KRAS通路的激活. 这种凝结物形成对于AR-V7至关重要.

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