补充饮食的多样性和早期食物过敏风险
Stina Bodén1, Anna Lindam2, Carina Venter3,4
1Department of Clinical Sciences, Pediatrics, Umeå University, Umeå, Sweden.
概括
婴儿时期的多样化饮食,特别是在9个月前,显著降低了患食物过敏 (FA) 的风险. 引入更多的食物,无论频率如何,也会降低FA的几率,强调早期饮食多样性的重要性.
科学领域:
- 儿童营养学 儿童营养学
- 免疫学 免疫学 免疫学
- 过敏研究 研究过敏
背景情况:
- 婴儿饮食多样性 (DD) 可能会防止早期食物过敏 (FA).
- 关于DD,包括食物消费频率如何影响FA风险的数据有限.
- 了解这些因素对于早期的过敏预防策略至关重要.
研究的目的:
- 研究饮食多样性措施与婴儿医生诊断的食物过敏风险之间的关联.
- 确定食物消费频率是否影响饮食多样性对食物过敏的保护作用.
- 探索早期饮食模式对食物过敏发展的潜在保护作用.
主要方法:
- 研究了一组2060名婴儿,评估6个月和/或9个月的饮食多样性,使用加权得分,食物数量和过敏性食物数量.
- 通过指导性非循环图指导的多变量逻辑回归模型被用于分析9个月和18个月内与医生诊断的FA的关联.
- 进行了敏感性和分层分析以完善发现,包括对患有湿疹或FA家族病史的儿童的子组分析.
主要成果:
- 9个月的高加权饮食多样性得分与18个月的FA几率下降61%有关.
- 在9个月内引入13-14种食物,无论频率如何,都与FA的几率下降45%有关.
- 在患有湿疹的儿童和没有家族病史的儿童中观察到减少了FA的几率,这表明特定的脆弱群体.
结论:
- 从9个月开始的多样化的饮食似乎是预防食物过敏的重要因素.
- 这些发现强调需要进一步研究食物消费频率在早期生活饮食模式和过敏预防中的具体作用.
- 婴儿期早期的饮食多样性是缓解食物过敏风险的有希望的途径.
相关概念视频
Cross-reactivity
30.9K
Overview
30.9K
Allergic Reactions
27.2K
Overview
27.2K
Complementation Tests
4.8K
A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
4.8K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
310
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
310
Hypersensitivities
491
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
491
Development of Immunocompetence
282
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
282


