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Updated: May 30, 2025

Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System
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APOBEC-1辅因子调节B型肝炎病毒中APOBEC3诱导的突变

Zhigang Chen1, Thomas L Eggerman1,2, Alexander V Bocharov1

  • 1Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

Journal of virology
|January 27, 2025
PubMed
概括

APOBEC3蛋白 (A3s) 对免疫和癌症至关重要. 这项研究表明,APOBEC-1 (A1) 辅因子和hNRNP调节A3突变活性,影响病毒防御和癌症突变.

关键词:
在 APOBEC3 中,APOBEC3 是一个辅助因素.乙型肝炎病毒的感染.在 hnRNP 中.过度突变是一种超级突变.突变是一种突变.监管 监管 监管 监管 监管 监管

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