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Updated: May 30, 2025

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基于植物化学的乳腺癌药物发现:将虚拟查和分子动力学结合起来,以确定新的治疗方法

Trupti Pratik Durgawale1, V Rajashakar2, Jeetendra Kumar Gupta3

  • 1Department of Pharmaceutical Chemistry, KVV's Krishna Institute of Pharmacy, Karad, India.

Chemistry & biodiversity
|January 27, 2025
PubMed
概括

研究人员确定了五种天然化合物作为母体胚胎白氨酸激酶 (MELK) 的潜在抑制剂,这是三阴性乳腺癌 (TNBC) 的关键标. 这些化合物显示出开发新型抗癌疗法对抗TNBC的前途.

关键词:
乳腺癌 乳腺癌 乳腺癌孕产妇胚胎氨酸拉链激酶 (MELK) 的使用分子动力学 (MD) 模拟植物化合物 植物化合物虚拟选 虚拟选 虚拟选

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