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一种新型的HTNV芽生长抑制剂干扰了病毒葡萄糖蛋白和宿主ESCRT辅助蛋白ALIX之间的相互作用

Qikang Ying1, Xiaoxiao Zhang1, Shengzheng Wang2

  • 1Department of Microbiology, School of Basic Medicine, Air Force Military Medical University, Xi'an, China.

Journal of medical virology
|January 27, 2025
PubMed
概括

一种新型化合物AN-329破坏了YRTL-ALIX相互作用,抑制了Hantaan病毒的产生. 这一发现为开发针对包裹RNA病毒的广泛抗病毒药物提供了有前途的战略.

关键词:
阿里克斯·阿里克斯 (ALIXIX) 是一个这是ESCRT的特点.奥尔托汉坦病毒 (Orthohantavirus) 存在于人体内.病毒包裹的病毒包裹.晚期域名 晚期域名

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