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Updated: May 30, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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在状细胞癌中,THG-1/TSC22D4通过稳定TRAF6促进IL-1信号传递

Yasuhito Okano1,2, Hiroyuki Suzuki1,3, Yukihide Watanabe1

  • 1Department of Experimental Pathology, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.

Molecular cancer research : MCR
|January 27, 2025
PubMed
概括

一种新型的瘤蛋白THG-1 (TSC22D4) 通过阻断TRAF6降解,推动瘤的进展和复发,维持平细胞癌 (SCC) 的慢性炎症. 这一发现为SCC诊断和免疫治疗提供了新的途径.

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