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Updated: May 30, 2025

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization
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Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Published on: February 27, 2020

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自动化高通量亲和度捕获-质谱平台与数据独立获取

Hui Jing1, Paul L Richardson1, Gregory K Potts1

  • 1Discovery Research, AbbVie, Inc., 1 North Waukegan Rd., North Chicago, Illinois 60064, United States.

Journal of proteome research
|January 27, 2025
PubMed
概括

我们开发了一种自动化的亲和度捕获-质谱工作流程,用于高通量药物标分析. 这种方法显著减少了样本准备时间,并提高了小分子选择性研究的激酶覆盖率.

关键词:
时间 时间 时间 时间自动化自动化自动化自动化化学蛋白质组学化学组学这是一种激酶抑制剂 (kinase inhibitor).这里是Kinome和Kinome.

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Tandem Mass Spectrometry

Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and signal-to-noise ratio for the analyte. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.
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Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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MALDI-TOF Mass Spectrometry

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Mass Spectrometry: Complex Analysis

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Mass Spectrometers

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