在美国成年人中开发和评估9个基于肥胖的胆结石指数
Xiaodong Wu1, Yanhong Song2, Shuodong Wu1
1Department of General Surgery.
International journal of surgery (London, England)
|January 27, 2025
概括
腰围和体重指数等肥胖指标与胆结石有关. 相对脂肪质量 (RFM) 显示出识别胆结石风险的最强预测能力.
科学领域:
- 消化系统疾病与营养
- 肥胖和代谢健康 肥胖和代谢健康
- 诊断生物标志物 诊断生物标志物
背景情况:
- 胆结石是一个重大的全球健康问题,影响全球的消化健康.
- 肥胖是已知的危险因素,但对胆结石各种肥胖指标的比较预测值需要进一步调查.
研究的目的:
- 调查9个与肥胖相关的指标与胆结石之间的关联.
- 为了比较这些指标对胆结石查的预测性能.
主要方法:
- 利用了2017-2020年NHANES周期的数据.
- 使用加权后勤回归和ROC曲线分析来评估关联和预测能力.
- 进行了子组分析,以探索特定人群的风险.
主要成果:
- 六个指标 (BRI,RFM,BMI,WC,LAP,CMI) 被确定为胆结石的独立风险因素.
- 相对脂肪量 (RFM) 显示出最高的预测准确度 (AUC=0.70),显著超过其他指标.
- 观察到RFM和胆结石之间的线性正相关性,特别是在特定的人口和临床子组.
结论:
- RFM,BRI,BMI,WC,LAP和CMI对于胆结石的识别至关重要.
- 与其他评估指标相比,RFM成为胆结石的优越预测指标.
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