狗群中 Bordetella bronchiseptica 的同时感染:系统性审查和元分析
Ji Young Jang1, Dona Lee2, Se Yeol Oh3
1Department of Infectious Disease, College of Veterinary Medicine, Seoul National University, Seoul, Korea.
Veterinary immunology and immunopathology
|January 27, 2025
概括
与 Bordetella bronchiseptica 的同时感染在狗感染性呼吸道疾病 (CIRD) 中很常见. 这项研究强调了需要联合疫苗和普遍预防策略,以更好地管理犬咳.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 狗的健康 狗的健康
背景情况:
- 淋巴菌是导致犬感染性呼吸道疾病 (CIRD) 的主要原因之一.
- 在CIRD中,B. bronchiseptica的流行病学和共感染模式尚不清楚.
- 数据有限阻碍了对这种病原体的有效管理和控制策略.
研究的目的:
- 系统地审查和分析狗中B. bronchiseptica共感染的流行情况.
- 为了确定这些共感染的相关风险因素.
- 为改善CIRD管理提供见解.
主要方法:
- 在PubMed,Scopus,Web of Science和Embase进行了全面的系统文献搜索.
- 数据提取的重点是同时感染的流行率,确定的病原体,研究期,位置,庇护所类型和年龄.
- 对来自26项选定的研究的数据进行了元分析.
主要成果:
- 在CIRD中,B. bronchiseptica联合感染的总体患病率为47%.
- 在20世纪70年代的研究中,同时感染率明显高于20世纪70年代的研究 (77%),而不是21世纪的研究 (45%).
- Mycoplasma和狗呼吸道冠状病毒 (CRCoV) 经常被确定为共感染病原体.
结论:
- 与B. bronchiseptica相关的同时感染在狗感染性呼吸道疾病中很普遍.
- 显然需要开发针对多种病原体的联合疫苗.
- 建议针对不同环境和年龄组采取普遍的预防和控制策略.
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