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Updated: May 15, 2026

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为什么微塑料会加剧胆固醇性肝病? 通过NLRP3介导的肠道屏障完整性损伤物质

Siwen Li1, Yu Yuan1, Yuan Zeng1

  • 1Department of Health Toxicology, Xiangya School of Public Health, Central South University, Changsha, 410013, PR China.

Environmental pollution (Barking, Essex : 1987)
|January 27, 2025
PubMed
概括

聚烯微塑料 (PS-MPs) 通过破坏肠道屏障并激活NLRP3炎症,使胆固醇性肝病 (CLD) 恶化. 抑制NLRP3可以减少PS-MP诱导的肝损伤和肠损伤,这表明它是治疗点.

关键词:
胆固醇性肝病 (CLD) 是一种肝病.炎症 炎症是一种炎症.肠道屏障的完整性 肠道屏障的完整性在NOD-Like受体蛋白3 (NLRP3) 中.聚烯微塑料 (PS-MPs) 是一种聚烯微塑料.

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