ASD混合成分的分子可混合性:对固态NMR光谱和放松度的评估 (固态NMR光谱和放松度的附加值)

Lennert Cools1, Elien Derveaux2, Peter Adriaensens2

  • 1Drug Delivery and Disposition, KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Campus Gasthuisberg ON2, Herestraat 49 b921, 3000 Leuven, Belgium; Hasselt University, Institute for Materials Research (imo-imomec), Applied and Analytical Chemistry, NMR group, Martelarenlaan 42, 3500 Hasselt, Belgium.

PubMed
概括

评估无形固体分散 (ASD) 稳定性需要评估组件的可混合性. 固态核磁共振 (ssNMR) 技术,特别是ssNMR放松度,对此非常强大,提供了比调制微分扫描热度计 (mDSC) 优越的nm尺度洞察力.

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