美国人口中烟雾暴露和胆结石之间的性相关关系:一个横截面研究
Xingyong Huang1, Xuanyu Hao1, Tingting Wang1
1Department of Gastroenterology, Endoscopic Center, Engineering Research Center of Ministry of Education for Minimally Invasive, Gastrointestinal Endoscopic Techniques, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang, 110004, Liaoning Province, China.
BMC public health
|January 28, 2025
概括
吸烟和高血清丁水平是胆结石的危险因素,特别是在女性中. 这项研究强调,需要进一步研究戒烟策略,以预防女性胆结石的发展.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 胆结石 (胆结石) 造成严重的健康和经济负担,女性更容易受到影响.
- 吸烟对胆结石发展的影响仍在争论中,研究对性别影响的差异化研究有限.
研究的目的:
- 调查吸烟暴露与男性和女性胆结石发育之间的关联.
- 为了确定吸烟状态和血清中胆色素水平是否是胆结石的独立风险因素,按性别分层.
主要方法:
- 对2017-2020年国家健康和营养检查调查 (NHANES) 数据的横截面分析.
- 包括20岁及以上的参与者,他们有完整的吸烟状况数据,血清胆胺和胆结石病史.
- 后勤回归模型用于评估吸烟,丁胺水平和胆结石之间的关联,根据性别对子组进行分析.
主要成果:
- 总共有6982名参与者被分析;6.2%的男性和14.5%的女性报告了胆结石.
- 吸烟和较高的血清胆固醇含量 (≥3 ng/mL或0.05-2.99 ng/mL) 与女性胆结石发生率的增加有显著相关性.
- 在男性中,吸烟和胆结石之间没有统计学意义上的关联.
结论:
- 吸烟和血清上升的胆胺水平被确定为胆结石发展的潜在危险因素,特别是在女性中.
- 这些发现强调了考虑吸烟作为女性胆结石的可修改风险因素的重要性.
- 建议进行进一步的大规模前性研究,以验证这些性别相关性,并为预防策略提供信息.
相关概念视频
Genome-wide Association Studies-GWAS
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
Observational Studies
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One example of...
Statistical Methods for Analyzing Epidemiological Data
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
Stress Prevention and Stress Management Techniques IV
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Cholecystitis
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...


