在健康的年轻成年男性中,液体摄入量,水分状态和皮质醇动态之间的关系
Mitchell E Zaplatosch1,2, Laurie Wideman1, Jessica McNeil1
1Department of Kinesiology, University of North Carolina at Greensboro, Greensboro, Mailing address: P.O. Box 26170 Greensboro, NC, 27402-6170, USA.
Comprehensive psychoneuroendocrinology
|January 28, 2025
概括
这项研究发现,年轻男性每日摄入液体,水分状态和每日皮质醇模式之间没有显著的联系. 补水标记物没有影响皮质醇动态,这表明在没有脱水的健康人群中没有相关性.
科学领域:
- 内分泌学 在内分泌学.
- 人体生理学 人体生理学
- 压力反应应激反应
背景情况:
- 之前的研究将液体摄入量和水分激素与单一时间点皮质醇水平联系起来.
- 补水对日常皮质醇动态的影响仍然未被探索.
- 这项研究研究了水分状态和习惯性液体摄入量与皮质醇动态之间的关系.
研究的目的:
- 评估水分状态 (科普丁,尿液度,尿量) 和习惯性流体摄入量与皮质醇动态之间的关联.
- 分析皮质醇动态,包括夜间皮质醇升高,唾液皮质醇峰值,皮质醇唤醒反应,曲线下的面积和白天皮质醇倾斜.
主要方法:
- 29名男性参与者提供了24小时尿液样本和空腹血液样本进行水分评估.
- 参与者记录了前三天的24小时液体摄入量,并提供了10个唾液样本用于皮质醇分析.
- 用各种指数分析皮质醇动态,并通过三分组和回归分析评估关系.
主要成果:
- 在任何皮质醇动态指标 (ΔCAR,AUCG,AUCI,峰值SCORT,NCR,DCS) 中,没有发现液体摄入组之间的显著差异.
- 总体液体摄入量 (TFI) 和可佩与任何测量的皮质醇动态没有关联.
- 尿液水化标志物与任何皮质醇动态测量没有关联,即使在控制身体活动,睡眠和身体脂肪百分比之后.
结论:
- 在没有脱水刺激的健康年轻男性中,液体摄入量和水分状态与皮质醇动态无关.
- 这些发现表明,在正常生理条件下,水分可能不是日常皮质醇模式的显著调节者.
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