相关实验视频
Updated: May 30, 2025

08:41
Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
9.0K
儿童白血病预防的肠道本能:针对父母和照顾者的微生物组向建议
Ersen Kameri1,2,3, Vera Helena Jepsen1, Pawel Stachura1,4
1Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Centre of Child and Adolescent Health, Heinrich-Heine-University, Düsseldorf, Germany.
Frontiers in public health
|January 28, 2025
概括
在新生儿中促进多样化的肠道微生物组可能会降低儿童急性淋巴细胞白血病 (ALL) 的风险. 早期的社会接触和其他环境因素影响肠道微生物群,影响ALL的发育,并为父母提供预防策略.
科学领域:
- 儿科瘤学 儿科瘤学
- 微生物组研究 微生物组研究
- 免疫学 免疫学 免疫学
背景情况:
- 儿童白血病,特别是急性淋巴细胞白血病 (ALL),是一种重要的儿科癌症.
- 人们越来越认识到肠道微生物组在免疫平衡中的作用,不成熟与ALL病变发生有关.
- 饮食,出生方式和早期暴露等环境因素塑造了肠道微生物群的组成.
研究的目的:
- 审查影响儿童肠道微生物组成的风险因素.
- 探索肠道微生物群多样性与ALL风险之间的联系.
- 通过微生物组调制确定儿童白血病预防策略.
主要方法:
- 文献综述总结了关于肠道微生物组和儿童ALL的证据.
- 分析影响肠道微生物群发育的环境因素.
- 对微生物群多样性和白血病风险的研究结果的综合.
主要成果:
- 环境因素显著改变肠道微生物群,影响儿童白血病风险.
- 肠道微生物群的多样性与ALL的发展有关.
- 早期生活中的暴露,包括社会接触,影响微生物组成.
结论:
- 调节肠道微生物组为预防儿童ALL提供了潜在的策略.
- 通过早期社会接触等简单措施促进微生物多样性可能会降低ALL风险.
- 基于证据的建议可以赋予父母和照顾者在白血病预防方面的权力.
相关概念视频
Combination Therapies and Personalized Medicine
4.8K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.8K
Targeted Cancer Therapies
7.4K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.4K
Bone Marrow Sampling and Transplants
277
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
277
Cancer Prevention
6.0K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.0K

