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纠正强迫症和神经性厌食症中认知不灵活性既不适度也不调节治疗效果:一项探索性研究
Boris van Passel1,2, Unna N Danner3,4, Alexandra E Dingemans5
1Overwaal Centre of Expertise for Anxiety Disorders, Obsessive Compulsive Disorder (OCD) and Posttraumatic Stress-Disorder (PTSD), Institution for Integrated Mental Health Care, Pro Persona, Nijmegen, Netherlands.
Frontiers in psychiatry
|January 28, 2025
概括
这项研究没有发现认知灵活性与强迫症 (OCD) 或神经性厌食症 (AN) 治疗成功之间的联系. 认知补救疗法 (CRT) 没有比对照干预更提高认知灵活性.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 强迫症 (OCD) 和神经性厌食症 (AN) 与认知灵活性受损有关,可能阻碍治疗.
- 在这些人群中,认知灵活性与治疗结果之间的关系存在有限的研究.
- 认知补救疗法 (CRT) 被探索为一种加强认知灵活性的干预措施.
研究的目的:
- 调查基线认知灵活性是否预测强迫症和AN的成年人治疗结果.
- 为了确定认知灵活性的变化是否会影响治疗的成功.
- 与对照干预相比,评估辅助CRT在改善认知灵活性方面的有效性.
主要方法:
- 一个随机控制的多中心试验的二次分析,其中包括71名强迫症成年人和61名AN.
- 参与者接受了10次CRT或专业注意力治疗 (SAT).
- 认知灵活性是通过Trail Making Test (TMT),颜色字干扰测试 (CWIT) 和细节和灵活性问卷 (DFlex) 来评估的.
主要成果:
- 基线认知灵活性在强迫症或AN中没有预测或适度治疗结果.
- 从基线到干预后认知灵活性的改善并没有影响治疗结果.
- 与SAT相比,CRT在认知灵活性方面没有显著改善.
结论:
- 这项研究发现认知灵活性措施与强迫症和AN治疗结果之间没有关联.
- 这些发现挑战了认知灵活性作为这些疾病变化的关键机制的假定作用.
- 需要进一步的研究,以了解强迫症和AN的认知功能和治疗反应之间的复杂关系.
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