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与衰老相关的肌肉退化对行走过程中的动态稳定的影响:一项肌肉骨计算机模拟研究

Shoma Kudo¹, Masahiro Fujimoto¹, Akinori Nagano²

¹Health and Medical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Kagawa, Japan.

Frontiers in bioengineering and biotechnology

|January 28, 2025

概括

老龄化会降低肌肉力量,影响行走的稳定性. 降低最大同位体肌肉力量最显著地影响了老年人的动态稳定性控制,告知了预防跌倒的策略.

科学领域:

生物力学生物力学
老年学是一门学科.
肌肉骨生理学肌肉骨生理学

背景情况:

衰老会损害骨肌肉的生理特性,影响行走过程中的动态稳定性.
与年龄相关的肌肉缺陷和步行稳定性控制之间的确切因果关系尚未完全理解.

研究的目的:

研究与年龄相关的骨肌属性缺陷对动态行走稳定性的影响.
为了确定哪些特定的肌肉属性缺陷最显著地影响行走过程中的动态稳定性.

主要方法:

使用2D肌肉骨模型与18个Hill类型肌肉模拟行走.
创建了五种模型:年轻成年人 (YA),年长成年人 (OA),以及减少最大同位体力 (∆F),收缩速度 (∆V) 和失活时间 (∆T) 的模型.
使用稳定性边际 (MoS) 评估动态稳定性.

主要成果:

老年人 (OA) 模型表现出比年轻人 (YA) 模型更大的稳定率 (MoS).
降低最大同位力力 (∆F) 的模型显示出比降低速度 (∆V) 或延长停用时间 (∆T) 的模型更大的MoS.
这表明,老年人能够获得更稳定的步态,而降低最大力量需要更大的步行稳定性.

结论:

与衰老相关的肌肉缺陷,特别是最大同位体肌肉力量的减少,会在走路时损害动态稳定控制.
这些发现强调了肌肉力量在维持步态稳定的关键作用.
结果可以为减少老年人群中跌倒风险的干预措施提供信息.

关键词:

老化的老化衰老的老化控制平衡,控制平衡的方法防摔防止跌倒预防跌倒步态分析步态分析稳定性边际 (MOS) 是指稳定性的边际.生理变化生理变化

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