相关实验视频
Updated: May 30, 2025
06:16
Preparation Of Gushukang GSK Granules for In Vivo and In Vitro Experiments
Published on: May 9, 2019
7.6K
基于成分的方法来创建药物清单,并支持细分数据细分
Daniel Mendoza1, Isca Amanda1, Lin Zhao2
1College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Health informatics journal
|January 28, 2025
概括
本研究介绍了一种基于成分的方法,可以自动生成准确的药物清单. 该方法在不同的药物术语和用例中展示了通用性,提供了一种可靠的方法来创建药物代码集.
科学领域:
- 药理学 药理学是指药理学的学科.
- 医疗信息学 医疗信息学
- 计算生物学 计算生物学
背景情况:
- 准确的药物清单对于患者护理和研究至关重要.
- 目前用于生成药物代码集的方法可能是劳动密集型的,容易出现错误.
- 越来越需要自动化,可靠的方法来创建最新的药物清单.
研究的目的:
- 为了证明以前开发的基于成分的方法用于自动化制造药物清单的可通用性.
- 在国家药物规范 (NDC) 中应用和验证这种方法,以生成阿片类药物和抗抑郁药物药物清单.
- 评估自动生成列表的准确性,完整性和最新性.
主要方法:
- 在国家药品规范 (NDC) 背景下,重新使用和应用基于成分的方法.
- 通过自动比较与精选和活跃药物数据库 (CDC,HEDIS,FDA,RxNorm) 验证生成的药物清单.
- 作为验证过程的一部分,包括手动医生审查.
主要成果:
- 基于成分的方法被证明可以在两个临床术语 (RxNorm和NDC) 中进行概括.
- 对于阿片类药物和抗抑郁药物药物代码集,都证明了高精度,可重复使用性和完整性.
- 该方法成功生成了最新且无错误的药物清单.
结论:
- 基于成分的自动化方法对于创建准确和全面的药物清单是有效的.
- 这种方法为生成临床清单的不太准确,数据驱动的方法提供了一个创新的替代方案.
- 这种方法对于支持患者对敏感药物信息的隐私至关重要.
相关概念视频
01:15Drug Dosage Regimen: Overview
3.4K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.4K
01:01Dosage Regimen: Fixed Dose
1.8K
Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
1.8K
01:02Prescription, Nonprescription and Orphan Drugs
683
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
683
01:26Drug Administration and Therapy Phases: Overview
406
Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
406
01:24Rational Dosage Regimen: Maintenance Dose and Loading Dose
3.8K
A rational dosage regimen considers a drug's pharmacokinetics, including its absorption, distribution, metabolism, and elimination from the body. By understanding these factors, the appropriate dosage can be determined, and the dosing schedule can be designed to achieve and maintain the desired therapeutic effect while minimizing adverse effects.
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
3.8K
01:18Routes of Drug Administration: Enteral
3.2K
Medications can be administered through the enteral route using liquids, capsules, or tablets.
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
Unlike sublingually drugs, drugs that are taken orally pass through the gastrointestinal (GI) tract and get metabolized by the liver. Once metabolized, the drug is absorbed into the systemic circulation, reaching different body parts via the bloodstream. However, while passing through the stomach,...
3.2K