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前列腺活检的有效性和安全性的元分析:跨关节和跨直肠方法之间的比较

Syah Mirsya Warli¹, Stivano Rizky Valentino Torry², Dhirajaya Dharma Kadar³

¹Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara - Haji Adam Malik General Hospital, Indonesia.

Urology research & practice

|January 28, 2025

概括

与跨直肠 (TR) 活检相比,跨直肠 (TP) 前列腺活检提供了较低的直肠出血和感染风险,癌症检测率相似. 这一发现有助于选择最佳的前列腺癌诊断程序.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
医疗成像医学成像

背景情况:

传统的前列腺活检方法在准确性方面存在局限性.
跨 (TP) 和跨直肠 (TR) 活检是诊断前列腺癌的关键程序.

研究的目的:

为了比较跨腹膜与跨直肠前列腺活检的有效性和风险.
通过程序性评估提高前列腺癌诊断的准确性.

主要方法:

在主要数据库 (PubMed,Embase,Web of Science,Cochrane Library) 进行了全面的文献搜索,截至2023年6月8日.
通过使用Review Manager软件分析了涉及80,133名患者的19个出版物的数据.
亚组分析评估了研究类型对结果的影响.

主要成果:

在TP和TR前列腺活检之间没有观察到癌症检测率的显著差异 (RD=0.03;P=.12).
与TR活检相比,TP活检显著降低了直肠出血 (OR=0.24;P<.001),发烧/尿路感染 (OR=0.28;P<.001) 和败血症 (OR=0.50;P=.02) 的风险.

结论:

跨关前列腺活检显示,癌症检测率与跨直肠活检相当.
由于直肠出血和感染率较低,TP活检提供了显著的安全优势.
建议进行进一步的研究,以优化前列腺癌的诊断方法.

关键词:

前列腺活检前列腺活检前列腺癌是前列腺癌.通过经经.一个跨直肠的.

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