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Qixiang Geng1,2, Zixuan Jiang1,2,3, Woong Sub Byun1,2

  • 1Department of Chemical and Systems Biology, Stanford Cancer Institute, School of Medicine Stanford University, Stanford, California 94305-6104, United States.

Journal of medicinal chemistry
|January 28, 2025
PubMed
概括

研究人员开发了针对素激酶1α (CK1α) 的新型分子降解剂 (MGD). 这一发现利用了谷物胺库查和药物化学来进行强效和选择性蛋白质降解.

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